Gut Microbiota–Obesity Link Clarified
Changes in diet can cause gut microbes to produce acetate, which in turn stimulates insulin secretion and obesity in rodents, scientists...
Copper may be key in Burning Fat
A new study is further burnishing copper’s reputation as an essential nutrient for human physiology. A research team led by a scientist...
RNA-Targeting CRISPR
Scientists identify a novel CRISPR system that zeroes in on single-stranded RNA. Much attention paid to the bacterial CRISPR/Cas9system...
Toward Targeted Therapies for Autoimmune Disorders
History often repeats itself. More than 100 years ago, one of the world’s leading immunologists, Nobel Laureate Paul Ehrlich, doubted the...
New Technique Helps Researchers Determine Developmental Origins of Cells
Summary HHMI scientists have pioneered the use of genome editing to trace lineage in living system. Genome editing of synthetic target...
Nanoparticles target, transform fat tissue
At a Glance Nanoparticles designed to target white fat and convert it to calorie-burning brown fat slowed weight gain in obese mice...
Investigational CDK4/6 Inhibitor Abemaciclib is Active Against a Range of Cancer Types
The investigational anticancer therapeutic abemaciclib (formerly LY2835219), which targets CDK4 and CDK6, showed durable clinical...
Antibiotics From Scratch
Researchers have devised an approach for synthesizing new macrolide antibiotics from simple chemical building blocks. Using this...
Staying a Step Ahead of Cancer New Generation of mTOR Inhibitors Aims to Combat Drug-Resistant Tumor
Summary HHMI scientists have designed a potential cancer therapy that uses a unique strategy to block a molecule that drives the growth...
“Magic Mushroom" Compound May Ease Depression
Summary Psilocybin led to an improvement in symptoms for treatment-resistant patients, according to a small study. So-called magic...
