A deep look inside the live cells reveals a key cancer process
Telomerase, a powerful enzyme found at the ends of chromosomes, can keep humans healthy, or promote cancer growth. Researchers at the...
Investigational CDK4/6 Inhibitor Abemaciclib is Active Against a Range of Cancer Types
The investigational anticancer therapeutic abemaciclib (formerly LY2835219), which targets CDK4 and CDK6, showed durable clinical...
Staying a Step Ahead of Cancer New Generation of mTOR Inhibitors Aims to Combat Drug-Resistant Tumor
Summary HHMI scientists have designed a potential cancer therapy that uses a unique strategy to block a molecule that drives the growth...
Genetic change to non-DNA structures in cell can cause cancer
A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new...
FDA Expands Use of Antiangiogenic to Kidney Cancer
Last week, the U.S. Food and Drug Administration (FDA) announced that it had approved the use of the antiangiogenic therapeutic...
FDA Expands Use of Molecularly Targeted Therapeutic for Lung Cancer
The U.S. Food and Drug Administration (FDA) recently approved the use of molecularly targeted therapeutic afatinib (Gilotrif) for...
Fighting Cancer With Killer T-Cells
Three companies are locked in a tight race to develop next-generation immuno-oncology treatments called chimeric antigen receptor T-cells...
Tumor-Shrinking Triple-Helices
A braided structure and some adhesive hydrogel make therapeutic microRNAs both stable and sticky. MicroRNAs (miRs) are small, noncoding...
Advances in Immunotherapy: Tackling CAR T-cell Therapy Resistance
In a study published in the AACR’s journal Cancer Discovery in December, a team of researchers from the Perelman School of Medicine and...
10 persistent cancer myths debunked
Google ‘cancer’ and you’ll be faced with millions of web pages. And the number of YouTube videos you find if you look up ‘cancer cure’ is...
